Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice

Glucagon supports glucose homeostasis by stimulating hepatic gluconeogenesis, in part by promoting the uptake and conversion of amino acids into gluconeogenic precursors. Genetic disruption or pharmacologic inhibition of glucagon signaling results in elevated plasma amino acids and compensatory gluc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Metab
Egile Nagusiak: Kim, Jinrang, Okamoto, Haruka, Huang, ZhiJiang, Anguiano, Guillermo, Chen, Shiuhwei, Liu, Qing, Cavino, Katie, Xin, Yurong, Na, Erqian, Hamid, Rachid, Lee, Joseph, Zambrowicz, Brian, Unger, Roger, Murphy, Andrew J., Xu, Yan, Yancopoulos, George D., Li, Wen-hong, Gromada, Jesper
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206958/
https://ncbi.nlm.nih.gov/pubmed/28591637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.05.006
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