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Hepatic Glucagon Signaling Regulates PCSK9 and LDL-Cholesterol

RATIONALE: Glucagon is a key hormone that regulates the adaptive metabolic responses to fasting. In addition to maintaining glucose homeostasis, glucagon participates in the regulation of cholesterol metabolism, however, the molecular pathways underlying this effect are incompletely understood. OBJE...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Spolitu, Stefano, Okamoto, Haruka, Dai, Wen, Zadroga, John A., Wittchen, Erika S., Gromada, Jesper, Ozcan, Lale
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457439/
https://ncbi.nlm.nih.gov/pubmed/30582457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313648
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