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Variation in PCSK9, Low LDL Cholesterol, and Risk of Peripheral Arterial Disease

BACKGROUND: We hypothesized that variants in PCSK9 that lower LDL cholesterol levels are associated with reduced prevalence and incidence of peripheral artery disease (PAD). METHODS: The Atherosclerosis Risk in Communities (ARIC) Study assessed risk factors and PCSK9 variants Y142X and C679X (releva...

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Detalhes bibliográficos
Main Authors: Folsom, Aaron R., Peacock, James M., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607475/
https://ncbi.nlm.nih.gov/pubmed/18436227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2008.03.009
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