Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer’s disease and Parkinson’s disease: Mendelian randomisation study

Objective To test the hypothesis that low density lipoprotein (LDL) cholesterol due to genetic variation in the genes responsible for LDL cholesterol metabolism and biosynthesis(PCSK9 and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), respectively) is associated with a high risk of Alzheimer’s di...

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Detaylı Bibliyografya
Yayımlandı:BMJ
Asıl Yazarlar: Benn, Marianne, Nordestgaard, Børge G, Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group Ltd. 2017
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421439/
https://ncbi.nlm.nih.gov/pubmed/28438747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.j1648
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