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Targeted inhibition of Polo‐like kinase 1 by a novel small‐molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells

Bladder cancer is a common cancer with particularly high recurrence after transurethral resection. Despite improvements in neoadjuvant chemotherapy, the outcome of patients with advanced bladder cancer has changed very little. In this study, the anti‐tumour activities of a novel Polo‐like kinase 1 (...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Zhe, Zhang, Guojun, Kong, Chuize
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345669/
https://ncbi.nlm.nih.gov/pubmed/27878946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13018
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