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Targeted inhibition of Polo‐like kinase 1 by a novel small‐molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells

Bladder cancer is a common cancer with particularly high recurrence after transurethral resection. Despite improvements in neoadjuvant chemotherapy, the outcome of patients with advanced bladder cancer has changed very little. In this study, the anti‐tumour activities of a novel Polo‐like kinase 1 (...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Zhang, Zhe, Zhang, Guojun, Kong, Chuize
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345669/
https://ncbi.nlm.nih.gov/pubmed/27878946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13018
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