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Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice
Genetic deficiency in TLR9 accelerates pathogenesis in the spontaneous polygenic MRL.Fas(lpr) murine model of systemic lupus erythematosus, despite the absence of anti-nucleosome autoantibodies. However, it could be argued that this result was dependent on Fas-deficiency rather than lupus-promoting...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344451/ https://ncbi.nlm.nih.gov/pubmed/28278279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173471 |
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