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Regulation of lupus-related autoantibody production and clinical disease by toll-like receptors
Autoantigens that contain DNA, RNA, or self-IgG are preferred targets for autoantibodies in Systemic Lupus Erythematosus (SLE). B cells promote SLE pathogenesis by: producing autoantibodies, activating autoreactive T cells, and secreting cytokines. We discuss how certain autoreactive B cells are sel...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709770/ https://ncbi.nlm.nih.gov/pubmed/17276080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2006.12.005 |
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