The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice

BACKGROUND AND PURPOSE: Peptides from venomous animals have long been important for understanding pain mechanisms and for the discovery of pain treatments. Here, we hypothesized that Phα1β, a peptide from the venom of the armed spider Phoneutria nigriventer, produces analgesia by blocking the TRPA1...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Br J Pharmacol
Huvudupphovsmän: Tonello, Raquel, Fusi, Camilla, Materazzi, Serena, Marone, Ilaria M, De Logu, Francesco, Benemei, Silvia, Gonçalves, Muryel C, Coppi, Elisabetta, Castro‐Junior, Celio J, Gomez, Marcus Vinicius, Geppetti, Pierangelo, Ferreira, Juliano, Nassini, Romina
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341489/
https://ncbi.nlm.nih.gov/pubmed/27759880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13652
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk