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Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies

Genome-wide association studies have identified thousands of variants implicated in dozens of complex diseases. Most studies collect individuals with and without disease and search for variants with different frequencies between the groups. For many of these studies, additional disease traits are al...

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書目詳細資料
發表在:Genetics
Main Authors: Bilow, Michael, Crespo, Fernando, Pan, Zhicheng, Eskin, Eleazar, Eyheramendy, Susana
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340321/
https://ncbi.nlm.nih.gov/pubmed/28132020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198473
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