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Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies

Genome-wide association studies have identified thousands of variants implicated in dozens of complex diseases. Most studies collect individuals with and without disease and search for variants with different frequencies between the groups. For many of these studies, additional disease traits are al...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Bilow, Michael, Crespo, Fernando, Pan, Zhicheng, Eskin, Eleazar, Eyheramendy, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340321/
https://ncbi.nlm.nih.gov/pubmed/28132020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198473
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