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Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies

Genome-wide association studies have identified thousands of variants implicated in dozens of complex diseases. Most studies collect individuals with and without disease and search for variants with different frequencies between the groups. For many of these studies, additional disease traits are al...

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Dades bibliogràfiques
Publicat a:Genetics
Autors principals: Bilow, Michael, Crespo, Fernando, Pan, Zhicheng, Eskin, Eleazar, Eyheramendy, Susana
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340321/
https://ncbi.nlm.nih.gov/pubmed/28132020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198473
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