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Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies

Genome-wide association studies have identified thousands of variants implicated in dozens of complex diseases. Most studies collect individuals with and without disease and search for variants with different frequencies between the groups. For many of these studies, additional disease traits are al...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Bilow, Michael, Crespo, Fernando, Pan, Zhicheng, Eskin, Eleazar, Eyheramendy, Susana
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340321/
https://ncbi.nlm.nih.gov/pubmed/28132020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198473
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