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Increasing Power of Genome-Wide Association Studies by Collecting Additional Single-Nucleotide Polymorphisms
Genome-wide association studies (GWASs) have been effectively identifying the genomic regions associated with a disease trait. In a typical GWAS, an informative subset of the single-nucleotide polymorphisms (SNPs), called tag SNPs, is genotyped in case/control individuals. Once the tag SNP statistic...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122306/ https://ncbi.nlm.nih.gov/pubmed/21467568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.128595 |
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