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Increasing Power of Genome-Wide Association Studies by Collecting Additional Single-Nucleotide Polymorphisms

Genome-wide association studies (GWASs) have been effectively identifying the genomic regions associated with a disease trait. In a typical GWAS, an informative subset of the single-nucleotide polymorphisms (SNPs), called tag SNPs, is genotyped in case/control individuals. Once the tag SNP statistic...

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Detalhes bibliográficos
Main Authors: Kostem, Emrah, Lozano, Jose A., Eskin, Eleazar
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122306/
https://ncbi.nlm.nih.gov/pubmed/21467568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.128595
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