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Effect of genome-wide simultaneous hypotheses tests on the discovery rate

An increasing number of genome-wide association studies are being performed in hundreds of thousands of single nucleotide polymorphisms (SNPs). Many of such studies carry on a second stage in which a selected number of SNPs are genotyped in new individuals in order to validate genome-wide findings....

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Main Authors: Eyheramendy, Susana, Gieger, Christian, Laan, Maris, Illig, Thomas, Meitinger, Thomas, Wichmann, Erich
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110391/
https://ncbi.nlm.nih.gov/pubmed/21686131
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