NAD(P)H Oxidase Nox-4 Mediates 7-Ketocholesterol-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Aortic Smooth Muscle Cells

The mechanisms involved in the cytotoxic action of oxysterols in the pathogenesis of atherosclerosis still remain poorly understood. Among the major oxysterols present in oxidized low-density lipoprotein, we show here that 7-ketocholesterol (7-Kchol) induces oxidative stress and/or apoptotic events...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Pedruzzi, Eric, Guichard, Cécile, Ollivier, Véronique, Driss, Fathi, Fay, Michèle, Prunet, Céline, Marie, Jean-Claude, Pouzet, Cécile, Samadi, Mohammad, Elbim, Carole, O'Dowd, Yvonne, Bens, Marcelle, Vandewalle, Alain, Gougerot-Pocidalo, Marie-Anne, Lizard, Gérard, Ogier-Denis, Eric
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC533993/
https://ncbi.nlm.nih.gov/pubmed/15572675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10703-10717.2004
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars