Interleukin-18 Primes the Oxidative Burst of Neutrophils in Response to Formyl-Peptides: Role of Cytochrome b558 Translocation and N-Formyl Peptide Receptor Endocytosis

Using flow cytometry, we observed that interleukin-18 (IL-18) primed human neutrophils (PMNs) in whole blood to produce superoxide anion (O(2)°(−)) in response to N-formyl peptide (fMLP) stimulation, whereas IL-18 alone had no significant effect. In contrast to tumor necrosis factor alpha (TNF-α), w...

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Main Authors: Elbim, Carole, Guichard, Cécile, Dang, Pham M. C.,  Fay, Michèle, Pedruzzi, Eric, Demur, Hélène, Pouzet, Cécile, El Benna, Jamel, Gougerot-Pocidalo, Marie-Anne
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Cellular Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065204/
https://ncbi.nlm.nih.gov/pubmed/15753257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.12.3.436-446.2005
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