NAD(P)H Oxidase Nox-4 Mediates 7-Ketocholesterol-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Aortic Smooth Muscle Cells

The mechanisms involved in the cytotoxic action of oxysterols in the pathogenesis of atherosclerosis still remain poorly understood. Among the major oxysterols present in oxidized low-density lipoprotein, we show here that 7-ketocholesterol (7-Kchol) induces oxidative stress and/or apoptotic events...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pedruzzi, Eric, Guichard, Cécile, Ollivier, Véronique, Driss, Fathi, Fay, Michèle, Prunet, Céline, Marie, Jean-Claude, Pouzet, Cécile, Samadi, Mohammad, Elbim, Carole, O'Dowd, Yvonne, Bens, Marcelle, Vandewalle, Alain, Gougerot-Pocidalo, Marie-Anne, Lizard, Gérard, Ogier-Denis, Eric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Cell Growth and Development
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC533993/
https://ncbi.nlm.nih.gov/pubmed/15572675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10703-10717.2004
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