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Heat Shock Protein gp96 Interacts with Protein Phosphatase 5 and Controls Toll-like Receptor 2 (TLR2)-mediated Activation of Extracellular Signal-regulated Kinase (ERK) 1/2 in Post-hypoxic Kidney Cells

Ischemia/reperfusion injury (IRI) induces an innate immune response, leading to an inflammatory reaction and tissue damage that have been attributed to engagement of the Toll-like receptor (TLR) 2 and 4. However, the respective roles of TLR2 and/or TLR4 in mediating downstream activation of mitogen-...

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Detalhes bibliográficos
Main Authors: Mkaddem, Sanae Ben, Werts, Catherine, Goujon, Jean-Michel, Bens, Marcelle, Pedruzzi, Eric, Ogier-Denis, Eric, Vandewalle, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673320/
https://ncbi.nlm.nih.gov/pubmed/19265198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808376200
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