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The formyl peptide fMLF primes platelet activation and augments thrombus formation

ESSENTIALS: The role of formyl peptide receptor 1 (FPR1) and its ligand, fMLF, in the regulation of platelet function, hemostasis, and thrombosis is largely unknown. Fpr1‐deficient mice and selective inhibitors for FPR1 were used to investigate the function of fMLF and FPR1 in platelets. N‐formyl‐me...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Salamah, Maryam F., Ravishankar, Divyashree, Vaiyapuri, Rajendran, Moraes, Leonardo A., Patel, Ketan, Perretti, Mauro, Gibbins, Jonathan M., Vaiyapuri, Sakthivel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617722/
https://ncbi.nlm.nih.gov/pubmed/31033193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14466
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