Soluble TREM2 induces inflammatory responses and enhances microglial survival

Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed in microglia in the brain. A soluble form of TREM2 (sTREM2) derived from proteolytic cleavage of the cell surface receptor is increased in the preclinical stages of AD and positively correlates with the a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Exp Med
Päätekijät: Zhong, Li, Chen, Xiao-Fen, Wang, Tingting, Wang, Zhe, Liao, Chunyan, Wang, Zongqi, Huang, Ruizhi, Wang, Daxin, Li, Xinxiu, Wu, Linbei, Jia, Lin, Zheng, Honghua, Painter, Meghan, Atagi, Yuka, Liu, Chia-Chen, Zhang, Yun-Wu, Fryer, John D., Xu, Huaxi, Bu, Guojun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2017
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339672/
https://ncbi.nlm.nih.gov/pubmed/28209725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160844
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