TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

Triggering Receptor Expressed on Myeloid cells 2 (TREM2), which is expressed on myeloid cells including microglia in the CNS, has recently been identified as a risk factor for Alzheimer's disease (AD). TREM2 transmits intracellular signals through its transmembrane binding partner DNAX-activati...

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Vydáno v:J Neurosci
Hlavní autoři: Zheng, Honghua, Jia, Lin, Liu, Chia-Chen, Rong, Zhouyi, Zhong, Li, Yang, Longyu, Chen, Xiao-Fen, Fryer, John D., Wang, Xin, Zhang, Yun-wu, Xu, Huaxi, Bu, Guojun
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320608/
https://ncbi.nlm.nih.gov/pubmed/28077724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2459-16.2017
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