TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities

The surface receptor triggering receptor expressed on myeloid cells 2 (TREM2) plays a crucial role in maintaining a multitude of microglial activities, such as survival, proliferation, migration, metabolism, inflammation, and phagocytosis. However, the molecular mechanisms underlying TREM2-mediated...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Zhaoji, Ning, Jinhuan, Zheng, Xiaoyuan, Meng, Jian, Han, Linkun, Zheng, Honghua, Zhong, Li, Chen, Xiao-Fen, Zhang, Xian, Luo, Hong, Can, Dan, Xu, Huaxi, Zhang, Yun-wu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442838/
https://ncbi.nlm.nih.gov/pubmed/32826884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02874-3
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