Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

BACKGROUND: TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer’s disease (AD) and other neurodegenerative diseases. While multiple studies support a role for TREM2 in microglial recruitment to amylo...

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發表在:Mol Neurodegener
Main Authors: Zhong, Li, Wang, Zongqi, Wang, Daxin, Wang, Zhe, Martens, Yuka A., Wu, Linbei, Xu, Ying, Wang, Kai, Li, Jianguo, Huang, Ruizhi, Can, Dan, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870375/
https://ncbi.nlm.nih.gov/pubmed/29587871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0247-7
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