Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

BACKGROUND: TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer’s disease (AD) and other neurodegenerative diseases. While multiple studies support a role for TREM2 in microglial recruitment to amylo...

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Библиографические подробности
Опубликовано в: :Mol Neurodegener
Главные авторы: Zhong, Li, Wang, Zongqi, Wang, Daxin, Wang, Zhe, Martens, Yuka A., Wu, Linbei, Xu, Ying, Wang, Kai, Li, Jianguo, Huang, Ruizhi, Can, Dan, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870375/
https://ncbi.nlm.nih.gov/pubmed/29587871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0247-7
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