Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

BACKGROUND: TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer’s disease (AD) and other neurodegenerative diseases. While multiple studies support a role for TREM2 in microglial recruitment to amylo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Neurodegener
Päätekijät: Zhong, Li, Wang, Zongqi, Wang, Daxin, Wang, Zhe, Martens, Yuka A., Wu, Linbei, Xu, Ying, Wang, Kai, Li, Jianguo, Huang, Ruizhi, Can, Dan, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870375/
https://ncbi.nlm.nih.gov/pubmed/29587871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0247-7
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