Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

BACKGROUND: TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer’s disease (AD) and other neurodegenerative diseases. While multiple studies support a role for TREM2 in microglial recruitment to amylo...

Full description

Saved in:
Bibliographic Details
Published in:Mol Neurodegener
Main Authors: Zhong, Li, Wang, Zongqi, Wang, Daxin, Wang, Zhe, Martens, Yuka A., Wu, Linbei, Xu, Ying, Wang, Kai, Li, Jianguo, Huang, Ruizhi, Can, Dan, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870375/
https://ncbi.nlm.nih.gov/pubmed/29587871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0247-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items