Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

Several heterozygous missense mutations in the triggering receptor expressed on myeloid cells 2 (TREM2) have recently been linked to risk for a number of neurological disorders including Alzheimer disease (AD), Parkinson disease, and frontotemporal dementia. These discoveries have re-ignited interes...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Atagi, Yuka, Liu, Chia-Chen, Painter, Meghan M., Chen, Xiao-Fen, Verbeeck, Christophe, Zheng, Honghua, Li, Xia, Rademakers, Rosa, Kang, Silvia S., Xu, Huaxi, Younkin, Steven, Das, Pritam, Fryer, John D., Bu, Guojun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646257/
https://ncbi.nlm.nih.gov/pubmed/26374899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679043
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