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DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response

Triggering receptor expressed on myeloid cells 2 (TREM2) is a DAP12-associated receptor expressed in microglia, macrophages, and other myeloid-derived cells. Previous studies have suggested that TREM2/DAP12 signaling pathway reduces inflammatory responses and promotes phagocytosis of apoptotic neuro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Zhong, Li, Chen, Xiao-Fen, Zhang, Zhen-Lian, Wang, Zhe, Shi, Xin-Zhen, Xu, Kai, Zhang, Yun-Wu, Xu, Huaxi, Bu, Guojun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505493/
https://ncbi.nlm.nih.gov/pubmed/25957402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645986
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