TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway

DNAX-activating protein of 12 kDa (DAP12) is a signaling adapter protein expressed in cells that participate in innate immune responses. By pairing with different triggering receptors expressed on myeloid cell (TREM) proteins, DAP12 can mediate both positive and negative cellular responses. In parti...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Zhong, Li, Zhang, Zhen-Lian, Li, Xinxiu, Liao, Chunyan, Mou, Pengfei, Wang, Tingting, Wang, Zongqi, Wang, Zhe, Wei, Min, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478682/
https://ncbi.nlm.nih.gov/pubmed/28680398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00204
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