TREM2 in CNS homeostasis and neurodegenerative disease

Myeloid-lineage cells accomplish a myriad of homeostatic tasks including the recognition of pathogens, regulation of the inflammatory milieu, and mediation of tissue repair and regeneration. The innate immune receptor and its adaptor protein—triggering receptor expressed on myeloid cells 2 (TREM2) a...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Painter, Meghan M., Atagi, Yuka, Liu, Chia-Chen, Rademakers, Rosa, Xu, Huaxi, Fryer, John D., Bu, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560063/
https://ncbi.nlm.nih.gov/pubmed/26337043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0040-9
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