A Dominant Role for CD8(+)-T-Lymphocyte Selection in Simian Immunodeficiency Virus Sequence Variation

CD8(+) T lymphocytes (CD8-TL) select viral escape variants in both human immunodeficiency virus and simian immunodeficiency virus (SIV) infections. The frequency of CD8-TL viral escape as well as the contribution of escape to overall virus diversification has not been assessed. We quantified CD8-TL...

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Bibliographic Details
Main Authors: O'Connor, David H., McDermott, Adrian B., Krebs, Kendall C., Dodds, Elizabeth J., Miller, Jacqueline E., Gonzalez, Edna J., Jacoby, Timothy J., Yant, Levi, Piontkivska, Helen, Pantophlet, Ralph, Burton, Dennis R., Rehrauer, William M., Wilson, Nancy, Hughes, Austin L., Watkins, David I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC533930/
https://ncbi.nlm.nih.gov/pubmed/15564508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.14012-14022.2004
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