A Dominant Role for CD8(+)-T-Lymphocyte Selection in Simian Immunodeficiency Virus Sequence Variation

CD8(+) T lymphocytes (CD8-TL) select viral escape variants in both human immunodeficiency virus and simian immunodeficiency virus (SIV) infections. The frequency of CD8-TL viral escape as well as the contribution of escape to overall virus diversification has not been assessed. We quantified CD8-TL...

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Autors principals: O'Connor, David H., McDermott, Adrian B., Krebs, Kendall C., Dodds, Elizabeth J., Miller, Jacqueline E., Gonzalez, Edna J., Jacoby, Timothy J., Yant, Levi, Piontkivska, Helen, Pantophlet, Ralph, Burton, Dennis R., Rehrauer, William M., Wilson, Nancy, Hughes, Austin L., Watkins, David I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC533930/
https://ncbi.nlm.nih.gov/pubmed/15564508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.14012-14022.2004
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