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Consequences of Cytotoxic T-Lymphocyte Escape: Common Escape Mutations in Simian Immunodeficiency Virus Are Poorly Recognized in Naïve Hosts

Cytotoxic T lymphocytes (CTL) are associated with control of immunodeficiency virus infection but also select for variants that escape immune recognition. Declining frequencies of epitope-specific CTL frequencies have been correlated with viral escape in individual hosts. However, escape mutations m...

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書誌詳細
主要な著者: Friedrich, Thomas C., McDermott, Adrian B., Reynolds, Matthew R., Piaskowski, Shari, Fuenger, Sarah, de Souza, Ivna P., Rudersdorf, Richard, Cullen, Candice, Yant, Levi J., Vojnov, Lara, Stephany, Jason, Martin, Sarah, O'Connor, David H., Wilson, Nancy, Watkins, David I.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC515024/
https://ncbi.nlm.nih.gov/pubmed/15331739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.18.10064-10073.2004
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