A Dominant Role for CD8(+)-T-Lymphocyte Selection in Simian Immunodeficiency Virus Sequence Variation

CD8(+) T lymphocytes (CD8-TL) select viral escape variants in both human immunodeficiency virus and simian immunodeficiency virus (SIV) infections. The frequency of CD8-TL viral escape as well as the contribution of escape to overall virus diversification has not been assessed. We quantified CD8-TL...

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Autori principali: O'Connor, David H., McDermott, Adrian B., Krebs, Kendall C., Dodds, Elizabeth J., Miller, Jacqueline E., Gonzalez, Edna J., Jacoby, Timothy J., Yant, Levi, Piontkivska, Helen, Pantophlet, Ralph, Burton, Dennis R., Rehrauer, William M., Wilson, Nancy, Hughes, Austin L., Watkins, David I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC533930/
https://ncbi.nlm.nih.gov/pubmed/15564508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.14012-14022.2004
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