Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice

BACKGROUND: The B cell receptor TACI is important for T-independent antibody responses. One in 200 blood donors are heterozygous for the TACI A181E mutation. OBJECTIVE: To investigate the impact on B cell function of TACI A181E heterozygosity in reportedly healthy subjects and of the corresponding T...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Allergy Clin Immunol
Main Authors: Jabara, Haifa H., Lee, John J., Janssen, Erin, Ullas, Sumana, Liadaki, Kyriaki, Garibyan, Lilit, Benson, Halli, Sannikova, Tatyana, Bram, Richard, Hammarstrom, Lennart, Cruz, Anthony C., Siegel, Richard, Manis, John, Malley, Richard, Geha, Raif S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337448/
https://ncbi.nlm.nih.gov/pubmed/27609654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.07.028
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker