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TLR9, TACI and CD40 synergize in causing B cell activation
BACKGROUND: B cells receive activating signals from T cells via CD40, from microbial DNA via TLR9, and from dendritic cells (DCs) via transmembrane activator calcium modulator and cyclophilin ligand interactor (TACI). TLR9 and CD40 ligation augment TACI driven B cell activation, but only the mechani...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164940/ https://ncbi.nlm.nih.gov/pubmed/21741080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.04.052 |
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