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TACI drives plasma cell differentiation in LPS activated B cells

BACKGROUND: TACI expression on B cells is upregulated by TLR4. OBJECTIVE: To examine whether TACI synergizes with TLR4 in driving immunoglobulin (Ig) production by B cells and to examine the mechanism of this synergy. METHODS: Purified mouse naïve B cells were stimulated with the TACI ligand APRIL a...

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Autores principales: Ozcan, Esra, Garibyan, Lilit, Lee, John Jhe-Yun, Bram, Richard J., Lam, Kong-Peng, Geha, Raif S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693462/
https://ncbi.nlm.nih.gov/pubmed/19427685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.03.019
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