A carregar...
TRIF signaling is essential for TLR4-driven IgE class switching
The TLR4 ligand LPS causes mouse B cells to undergo IgE and IgG1 isotype switching in the presence of IL-4. TLR4 activates two signaling pathways mediated by the adaptor molecules MyD88 and TRAM, which recruits TRIF. Following stimulation with LPS+IL-4, Tram(−/−) and Trif(−/−) B cells completely fai...
Na minha lista:
| Main Authors: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952935/ https://ncbi.nlm.nih.gov/pubmed/24532577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300909 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|