Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells.

There is controversy as to whether deletional rearrangement occurs between the IgM and IgE switch regions (S mu and S epsilon, respectively) during switching to the IgE isotype. We have addressed the issue by stimulating normal human B cells, sorted for lack of expression of surface IgE, to produce...

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Main Authors: Shapira, S K, Jabara, H H, Thienes, C P, Ahern, D J, Vercelli, D, Gould, H J, Geha, R S
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52334/
https://ncbi.nlm.nih.gov/pubmed/1881893
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