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Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice
BACKGROUND: The B cell receptor TACI is important for T-independent antibody responses. One in 200 blood donors are heterozygous for the TACI A181E mutation. OBJECTIVE: To investigate the impact on B cell function of TACI A181E heterozygosity in reportedly healthy subjects and of the corresponding T...
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| 出版年: | J Allergy Clin Immunol |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5337448/ https://ncbi.nlm.nih.gov/pubmed/27609654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.07.028 |
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