Nalaganje...
ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data
Next-generation sequencing (NGS) of bulk tumour tissue can identify constituent cell populations in cancers and measure their abundance. This requires computational deconvolution of allelic counts from somatic mutations, which may be incapable of fully resolving the underlying population structure....
Shranjeno v:
| izdano v: | Genome Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333399/ https://ncbi.nlm.nih.gov/pubmed/28249593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1169-3 |
| Oznake: |
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