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PyClone-VI: scalable inference of clonal population structures using whole genome data

BACKGROUND: At diagnosis tumours are typically composed of a mixture of genomically distinct malignant cell populations. Bulk sequencing of tumour samples coupled with computational deconvolution can be used to identify these populations and study cancer evolution. Existing computational methods for...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Autores principales: Gillis, Sierra, Roth, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730797/
https://ncbi.nlm.nih.gov/pubmed/33302872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03919-2
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