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PyClone-VI: scalable inference of clonal population structures using whole genome data

BACKGROUND: At diagnosis tumours are typically composed of a mixture of genomically distinct malignant cell populations. Bulk sequencing of tumour samples coupled with computational deconvolution can be used to identify these populations and study cancer evolution. Existing computational methods for...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Bioinformatics
Prif Awduron: Gillis, Sierra, Roth, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730797/
https://ncbi.nlm.nih.gov/pubmed/33302872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03919-2
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