ReMixT: clone-specific genomic structure estimation in cancer

Somatic evolution of malignant cells produces tumors composed of multiple clonal populations, distinguished in part by rearrangements and copy number changes affecting chromosomal segments. Whole genome sequencing mixes the signals of sampled populations, diluting the signals of clone-specific aberr...

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Detaylı Bibliyografya
Yayımlandı:Genome Biol
Asıl Yazarlar: McPherson, Andrew W., Roth, Andrew, Ha, Gavin, Chauve, Cedric, Steif, Adi, de Souza, Camila P. E., Eirew, Peter, Bouchard-Côté, Alexandre, Aparicio, Sam, Sahinalp, S. Cenk, Shah, Sohrab P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530528/
https://ncbi.nlm.nih.gov/pubmed/28750660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1267-2
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