ReMixT: clone-specific genomic structure estimation in cancer

Somatic evolution of malignant cells produces tumors composed of multiple clonal populations, distinguished in part by rearrangements and copy number changes affecting chromosomal segments. Whole genome sequencing mixes the signals of sampled populations, diluting the signals of clone-specific aberr...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: McPherson, Andrew W., Roth, Andrew, Ha, Gavin, Chauve, Cedric, Steif, Adi, de Souza, Camila P. E., Eirew, Peter, Bouchard-Côté, Alexandre, Aparicio, Sam, Sahinalp, S. Cenk, Shah, Sohrab P.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530528/
https://ncbi.nlm.nih.gov/pubmed/28750660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1267-2
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