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nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing

Complex genomic rearrangements (CGRs) are emerging as a new feature of cancer genomes. CGRs are characterized by multiple genomic breakpoints and thus have the potential to simultaneously affect multiple genes, fusing some genes and interrupting other genes. Analysis of high-throughput whole-genome...

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Detalhes bibliográficos
Main Authors: McPherson, Andrew, Wu, Chunxiao, Wyatt, Alexander W., Shah, Sohrab, Collins, Colin, Sahinalp, S. Cenk
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483554/
https://ncbi.nlm.nih.gov/pubmed/22745232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136572.111
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