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nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing

Complex genomic rearrangements (CGRs) are emerging as a new feature of cancer genomes. CGRs are characterized by multiple genomic breakpoints and thus have the potential to simultaneously affect multiple genes, fusing some genes and interrupting other genes. Analysis of high-throughput whole-genome...

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Autori principali: McPherson, Andrew, Wu, Chunxiao, Wyatt, Alexander W., Shah, Sohrab, Collins, Colin, Sahinalp, S. Cenk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483554/
https://ncbi.nlm.nih.gov/pubmed/22745232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136572.111
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