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Combinatorial algorithms for structural variation detection in high-throughput sequenced genomes

Recent studies show that along with single nucleotide polymorphisms and small indels, larger structural variants among human individuals are common. The Human Genome Structural Variation Project aims to identify and classify deletions, insertions, and inversions (>5 Kbp) in a small number of norm...

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Autors principals: Hormozdiari, Fereydoun, Alkan, Can, Eichler, Evan E., Sahinalp, S. Cenk
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704429/
https://ncbi.nlm.nih.gov/pubmed/19447966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.088633.108
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