Reverse the Resistance to PARP Inhibitors

One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating double-strand breaks in the genome. Therefore, the concept to block PARP enzymes by...

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Bibliografische gegevens
Gepubliceerd in:Int J Biol Sci
Hoofdauteurs: Kim, Yevgeniy, Kim, Aleksei, Sharip, Ainur, Sharip, Aigul, Jiang, Juhong, Yang, Qing, Xie, Yingqiu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2017
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332874/
https://ncbi.nlm.nih.gov/pubmed/28255272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17240
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