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Reverse the Resistance to PARP Inhibitors
One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating double-strand breaks in the genome. Therefore, the concept to block PARP enzymes by...
Gorde:
| Argitaratua izan da: | Int J Biol Sci |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Ivyspring International Publisher
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5332874/ https://ncbi.nlm.nih.gov/pubmed/28255272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17240 |
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