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Reverse the Resistance to PARP Inhibitors
One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating double-strand breaks in the genome. Therefore, the concept to block PARP enzymes by...
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| 出版年: | Int J Biol Sci |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Ivyspring International Publisher
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5332874/ https://ncbi.nlm.nih.gov/pubmed/28255272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.17240 |
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